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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1090192Generated: October 31, 2026

1-(p-Chlorobenzyl)-1-(4-fluorophenyl)hydrazine hydrochloride → 3-Methyl-4-[1-p-chlorobenzyl-5-fluoro-3-methylindol-2-yl]butanoic acid

https://huagongshe.com/reaction/1090192

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(p-Chlorobenzyl)-1-(4-fluorophenyl)hydrazine hydrochlorideHCID 14591242—
Reactant3-Methyl-4-oxoheptanoic acidHCID 19914762—
SolventIsopropanolHCID 3776—
Product3-Methyl-4-[1-p-chlorobenzyl-5-fluoro-3-methylindol-2-yl]butanoic acidHCID 15678780—

Reaction Steps

Following the method of Example 2, but using 1-[(4-chlorophenyl)methyl]-1-(4-fluorophenyl)hydrazine hydrochloride and 3-methyl-4-oxoheptanoic acid as the starting materials and isopropanol as the solvent, the title compound was prepared.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05081145
Source datasetuspto-grants-1992_01
ORD IDord-b33b2a36164c468695024f70a7a5f7c4
Source noteuspto-grants-1992_01