HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(p-Chlorobenzyl)-1-(4-fluorophenyl)hydrazine hydrochloride → 4-[1-(4-chlorobenzyl)-5-fluoro-3-methyl-1H-indol-2-yl]-2,2-dimethyl butanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(p-Chlorobenzyl)-1-(4-fluorophenyl)hydrazine hydrochloride | HCID 14591242 | — |
| Reactant | Methyl-2,2-dimethyl-5-oxoheptanoate | HCID 15678813 | — |
| Solvent | tert-Butanol | HCID 6386 | — |
| Product | 4-[1-(4-chlorobenzyl)-5-fluoro-3-methyl-1H-indol-2-yl]-2,2-dimethyl butanoic acid | HCID 15678815 | — |
Reaction Steps
Following the method of Example 2, but using 1-[4-chlorobenzyl]-1-[4-fluorophenyl]hydrazine hydrochloride and methyl-2,2-dimethyl-5-oxoheptanoate as starting materials, in t-butanol as solvent, the title compound was prepared.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05081145 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-7360fb6f55e24820a802199fbb4ce4f1 |
| Source note | uspto-grants-1992_01 |