Pyridine → Pyridine, 3-(4-aminobutyl)-

HRID 1090228Notes

Reaction equation

HRID 1090228 reaction equation
P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:2].[Br:15][C:16]1[C:17]2[C:18]3[C:22](=[CH:23][CH:24]=1)[NH:21][C:20](=O)[C:19]=3[CH:26]=[CH:27][CH:28]=2.[N:29]1C=CC=CC=1>>[N:21]1[CH:28]=[CH:27][CH:26]=[C:19]([CH2:18][CH2:22][CH2:23][CH2:24][NH2:29])[CH:20]=1.[Br:15][C:16]1[C:17]2[C:18]3[C:22](=[CH:23][CH:24]=1)[N:21]=[C:20]([SH:2])[C:19]=3[CH:26]=[CH:27][CH:28]=2

Participants

5

Reactant 3

HCID 1049PyridineHCID 14817Phosphorus sulfide (P2S5)HCID 7547635-Bromo-8-naphtholactam

Product 2

HCID 72927Pyridine, 3-(4-aminobutyl)-HCID 178527759HCID 178527759, compound

Procedure

4-(3-Pyridinyl)butylamine was prepared by the procedure described in Helv. Chim. Acta. 65 1868-1883 (1982). 6-Bromobenz(cd)indol-2-thiol was prepared by the action of P2S5 upon 6-bromobenz(cd)indol-2-one in refluxing pyridine.

Sources & evidence

ORD record
ord-16cea23ece1a42acb1ada6a611c11f22
Source dataset
uspto-grants-1992_01
Patent number
US05081131

Reaction notes

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