HuagongsheHuagongshe Chemistry Print Report · For research reference only
Octanoic Acid → N-[3-(1H-Imidazol-1-yl)propyl]octanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Octanoic Acid | HCID 379 | — |
| Reactant | 1H-Imidazole-1-propanamine | HCID 78736 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-[3-(1H-Imidazol-1-yl)propyl]octanamide | HCID 5071006 | — |
Reaction Steps
The requisite starting amine was prepared as follows: reaction of n-octanoic acid and 1,1'-carbonyldi(1-imidazole) in tetrahydrofuran solution with 3-(1H-imidazol-1-yl)propanamine gave N-3-(1H-imidazolyl) propyl-n-octanamide, which upon reduction with BH3 in tetrahydrofuran solution gave N-(3-(1H-imidazol-1-yl) propyl-N-(n-octyl))amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05081131 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-4ac876970a7f4fc58cc2b891385d2d04 |
| Source note | uspto-grants-1992_01 |