HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indazole → Hydrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indazole | HCID 9221 | — |
| Reactant | N-3-Bromopropylphthalimide | HCID 21611 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Hydrazine | HCID 9321 | — |
| Product | HCID 19914595 | HCID 19914595 | — |
Reaction Steps
The reaction of the sodium salt of indazole with N-(3-bromopropyl)phthalimide in dimethylformamide solution gives N-(3-(1H-indazol-1-yl)propyl)phthalimide, which upon treatment with hydrazine in refluxing ethanol leads to (3-(1H-indazol-1-yl)propanamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05081131 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-ef9907ac7a374042843984db435467c5 |
| Source note | uspto-grants-1992_01 |