2-Amino-3-methylpyridine → HCID 11063074, compound

HRID 1090295Notes

Reaction equation

HRID 1090295 reaction equation
C(O[CH:4]=[C:5]([C:8]#[N:9])[C:6]#[N:7])C.[NH2:10][C:11]1[C:16]([CH3:17])=[CH:15][CH:14]=[CH:13][N:12]=1>C(O)C>[C:6]([C:5]1[C:8](=[NH:9])[N:12]2[CH:13]=[CH:14][CH:15]=[C:16]([CH3:17])[C:11]2=[N:10][CH:4]=1)#[N:7]

Participants

4

Reactant 2

HCID 153472-Amino-3-methylpyridineHCID 671522-(Ethoxymethylene)propanedinitrile

Product 1

HCID 11063074HCID 11063074, compoundYield 76%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To 200 ml of ethanol were added 11.8 g (97 mmoles) of ethoxymethylenemalononitrile and 10.5 g (97 mmoles) of 2-amino-3-methylpyridine, and the reaction was carried out with stirring at room temperature for 2 hours. After completion of the reaction, the crystals precipitated were collected by filtration to obtain 13.5 g of 3-cyano-4-imino-9-methyl-4H-pyrido[1,2-a]pyrimidine. Yield: 76%.

Workup

  1. customAfter completion of the reaction
  2. customthe crystals precipitated
  3. filtrationwere collected by filtration

Sources & evidence

ORD record
ord-32c675002f54459ba0a1c3ef88bdb7b7
Source dataset
uspto-grants-1992_01
Patent number
US05081243

Reaction notes

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