反应详情

温度

50 °C

To 3.26 g (10.4 mmol) of (-)-3-t-butyldimethylsilyloxybutyric acid phenylthio ester was added 50 ml of acetic acid: THF:water (3:1:1) and the mixture was stirred at 50° C. for 24 hours. The resultant was concentrated and distilled (128° to 130° C./0.8 mmHg) to give 1.91 g of (-)-3-hydroxybutyric acid phenylthio ester (yield: 94%).

1. concentrationThe resultant was concentrated
2. distillationdistilled (128° to 130° C./0.8 mmHg)