Hydrochloric Acid → HCID 67916266, compound

HRID 1090396Notes

Reaction equation

HRID 1090396 reaction equation
[CH:1]1([N:4]2[C:13]3[C:8](=[CH:9][C:10]([F:21])=[C:11]([CH:14]4[CH2:19][CH2:18][N:17]([CH3:20])[CH2:16][CH2:15]4)[CH:12]=3)[C:7](=[O:22])[C:6]([C:23]([O:25]CC)=[O:24])=[CH:5]2)[CH2:3][CH2:2]1.[ClH:28]>>[ClH:28].[CH:1]1([N:4]2[C:13]3[C:8](=[CH:9][C:10]([F:21])=[C:11]([CH:14]4[CH2:19][CH2:18][N:17]([CH3:20])[CH2:16][CH2:15]4)[CH:12]=3)[C:7](=[O:22])[C:6]([C:23]([OH:25])=[O:24])=[CH:5]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 14770859HCID 14770859, compound

Product 1

HCID 67916266HCID 67916266, compound

Procedure

A solution of 3.71 g (10 mmoles) of ethyl 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(1-methyl-4-piperidinyl)-4-oxo-3-quinolinecarboxylate in 50 ml 6 N HCl was refluxed 1 hour and evaporated to dryness to afford the title compound.

Workup

  1. customevaporated to dryness

Sources & evidence

ORD record
ord-082cd7b63c214cbb9bf71e4d349a86de
Source dataset
uspto-grants-1992_01
Patent number
US05081254

Reaction notes

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