Water → HCID 12884911, compound

HRID 1090432Notes

Reaction equation

HRID 1090432 reaction equation
[CH3:1][Ge:2]([CH3:20])([CH3:19])[C:3]1[CH:4]=[C:5]([C:13]2([CH3:18])OCC[O:14]2)[CH:6]=[C:7]([Ge:9]([CH3:12])([CH3:11])[CH3:10])[CH:8]=1.CC1C=CC(S([O-])(=O)=O)=CC=1.C1C=C[NH+]=CC=1.O>CC(C)=O>[CH3:11][Ge:9]([CH3:10])([CH3:12])[C:7]1[CH:6]=[C:5]([C:13](=[O:14])[CH3:18])[CH:4]=[C:3]([Ge:2]([CH3:19])([CH3:1])[CH3:20])[CH:8]=1

Participants

5

Reactant 3

HCID 962WaterHCID 466102Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1)HCID 128849082-(3,5-Bis(trimethylgermyl)phenyl]-2-methyl-1,3-dioxolane

Product 1

HCID 12884911HCID 12884911, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 240 mg (0.60 mmol) of 2-[3,5-bis(trimethylgermyl)phenyl]-2-methyl-1,3-dioxolane, 23 mg (0.090 mmol) of PPTS, 10.6 ml of acetone (excess) and 540 mg (30 mmol) of water was refluxed for 2.5hours. The reaction mixture was evaporated and extracted with ether. The extract was evaporated to give 208 mg of pale yellow crystals, which were sublimed at 70° C., 0.5mmHg to give 189 mg of white prisms, m.p.56° C. (yield 89%).

Workup

  1. temperaturewas refluxed for 2.5hours
  2. customThe reaction mixture was evaporated
  3. extractionextracted with ether
  4. customThe extract was evaporated

Sources & evidence

ORD record
ord-ab7679dd669e495dbed1b9f9d2c0f56e
Source dataset
uspto-grants-1992_01
Patent number
US05081271

Reaction notes

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