HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diphenyl Ether → 3-butyryl-8-phthalimido-4(1H)quinolone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diphenyl Ether | HCID 7583 | — |
| Reactant | HCID 178450491 | HCID 178450491 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | 3-butyryl-8-phthalimido-4(1H)quinolone | HCID 10338561 | — |
Reaction Steps
Ethyl 2-butyryl-3-(2-phthalimidophenylamino)acrylate (83 g, 0.2 mol) was added portionwise to boiling diphenyl ether and heated under reflux for 45 mins. The mixture was cooled, diluted with hexane and the 3-butyryl-8-phthalimido-4(1H)quinolone (50 g, 67.5%) filtered off, washed with hexane and dried, m.p. 318°-20° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05082841 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-4efe4ade941d48beb5e6e8dc60e473da |
| Source note | uspto-grants-1992_01 |