反应详情

Ethyl 2-butyryl-3-(2-phthalimidophenylamino)acrylate (83 g, 0.2 mol) was added portionwise to boiling diphenyl ether and heated under reflux for 45 mins. The mixture was cooled, diluted with hexane and the 3-butyryl-8-phthalimido-4(1H)quinolone (50 g, 67.5%) filtered off, washed with hexane and dried, m.p. 318°-20° C.

1. temperatureheated
2. temperatureunder reflux for 45 mins
3. temperatureThe mixture was cooled
4. filtrationthe 3-butyryl-8-phthalimido-4(1H)quinolone (50 g, 67.5%) filtered off
5. washwashed with hexane
6. customdried