HCID 15676952, compound → 2-Methoxyethyl piperidin-4-ylcarbamate

Participants

Reaction Steps

2-Methoxyethyl (1-phenylmethyl-4-piperidyl)carbamate (9.6 g), prepared according to Preparation 3, was dissolved in ethyl acetate (100 mL). Palladium hydroxide (10% on carbon, 1 g) was added, and the mixture was stirred under hydrogen (1 bar) for 6 hours. The catalyst was removed by filtration, and the solvent evaporated to give 6.5 g of 2-methoxyethyl-4-piperidylcarbamate as an oil, which was used without further purification.

Provenance & Evidence