HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3,3-dimethoxypropanoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methyl 3,3-dimethoxypropionate | HCID 81924 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 3,3-dimethoxypropanoic Acid | HCID 10374504 | 79.1% |
Reaction Steps
50 g (0.33 mol.) of Methyl 3,3-dimethoxy-propanoate in 200 ml of 2N NaOH solution in water were refluxed 2 hours. After cooling the solution was acidified with hydrochloric acid then extracted two times with 200 ml of CH2Cl2. The extracts were dried on sodium sulfate and evaporated to leave 35 g (Yield=78%) of 3,3-dimethoxy-propanoic acid as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05082847 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-8da6dea0eb444563af2b044a97b7fe22 |
| Source note | uspto-grants-1992_01 |