Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 4-(quinolin-2-ylmethoxy)benzoic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Methyl 4-(2-quinolinylmethoxy)benzoate | HCID 19934817 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-(quinolin-2-ylmethoxy)benzoic Acid | HCID 9838552 | 65.5% |
반응 단계
5.00 g of methyl-4-(quinolin-2-ylmethoxy)benzoate is dissolved in 120 ml of ethanol and 90 ml of 1N sodium hydroxide and the mixture is stirred at room temperature for 4 days. The mixture is concentrated in vacuo to remove the ethanol. The residue is diluted with water, acidified to pH 6 and the resulting solid is filtered off and recrystallized from methanol to give 3.12 g 4-(quinolin-2-ylmethoxy)benzoic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05082849 |
| 출처 데이터셋 | uspto-grants-1992_01 |
| ORD ID | ord-813a8b5498a34ca9a99a75095311e39c |
| 출처 메모 | uspto-grants-1992_01 |