Glycol monoethyl ether → HCID 15020138, compound

HRID 1090934Notes

Reaction equation

[CH2:1]([O:3][CH2:4][CH2:5][OH:6])[CH3:2].[H-].[Na+].Br[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18]>>[C:17]([OH:19])(=[O:18])[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][O:6][CH2:5][CH2:4][O:3][CH2:1][CH3:2]

Participants

Reactant 3

HCID 8076Glycol monoethyl ether

HCID 24758Sodium hydride

HCID 5482758-Bromooctanoic acid

Product 1

HCID 15020138HCID 15020138, compound

Procedure

Illustratively, 2-butoxyethanol can be reacted with sodium hydride and the resulting alcoholate reacted with 6-bromohexanoic acid to give 7,10-dioxatetradecanoic acid. So also, 2-ethoxyethanol can be reacted with sodium hydride and the resulting alcoholate reacted with 8-bromooctanoic acid to provide 9,12-dioxatetradecanoic acid.

Sources & evidence

ORD record: ord-a7d791024f0749158239d41f4c5065f7
Source dataset: uspto-grants-1992_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05082967

Reaction notes

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