反应详情

To a stirred mixture of 11.3 g of the above benzamide, 150 ml of methanolic ammonia and 250 ml of methanol was added, in increments, 25 ml of 30% hydrogen peroxide. After standing overnight, the solid was collected, partially dissolved in 500 ml of hot acetonitrile and filtered. The filtrate was concentrated and chilled, giving 2.0 g of the desired product as white crystals, mp 185°-188° C.

1. customthe solid was collected
2. dissolutionpartially dissolved in 500 ml of hot acetonitrile
3. filtrationfiltered
4. concentrationThe filtrate was concentrated
5. temperaturechilled