HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[N-[3-(4-Nitrophenoxy)propyl]methylamino methyl]quinoxaline → 2-[N-[3-(4-Aminophenoxy)propyl]methylamino methyl]quinoxaline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[N-[3-(4-Nitrophenoxy)propyl]methylamino methyl]quinoxaline | HCID 15675891 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-[N-[3-(4-Aminophenoxy)propyl]methylamino methyl]quinoxaline | HCID 15675892 | 74% |
Reaction Steps
A mixture of 2-[N-[3-(4-nitrophenoxy)propyl]methylamino methyl]quinoxaline (1.75 g, 4.97 mmol) and PtO2 (0.14 g, 0.62 mmol) in ethanol (170 mL) was charged with 1 atmosphere H2 (g). After 30 minutes, the mixture was filtered through solka floc and concentrated to afford crude product which was purified by HPLC to yield 1.18 g (74%) of a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05084463 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-bc9730f8b7ea46dabd7e777afa25b717 |
| Source note | uspto-grants-1992_01 |