反应详情

N-[4-[2-Hydroxy-3-[methyl[(6-nitro-2-quinolinyl)methyl]amino]propoxy]phenyl]methanesulfonamide (1.20 g, 2.61 mmol) and PtO2 (0.120 g, 10% by wt.) were suspended in ethanol (100 mL) and the flask was charged with H2 (1 atm). After stirring for 6 hours, the mixture was filtered through a pad of solka floc and the filtrate was concentrated in vacuo to afford 1.00 g of product as a pale oil which was used directly in the next step.

1. additionthe flask was charged with H2 (1 atm)
2. filtrationthe mixture was filtered through a pad of solka floc
3. concentrationthe filtrate was concentrated in vacuo