1,4-Dioxane hydrochloride → HCID 66592243, compound

Participants

Reaction Steps

4N—HCl/1,4-dioxane (10 mL) was added to (1S,4S)-(−)-2-cyclopropyl-2,5-diazabicyclo[2.2.1]heptan-5-ylcarboxylic acid tert-butyl ester (4.46 g, 18.71 mmol), and the mixture was stirred for 7 hours at room temperature. The reaction liquor was concentrated under reduced pressure, to obtain the title compound (3.34 g, 85%) as an oily matter.

Provenance & Evidence