Hydrochloric Acid → HCID 57868321, compound

Participants

Reaction Steps

[4-[(Benzo[b]furan-3-ylcarbonyl)amino]-3-chlorophenyl]acetic acid ethyl ester (2.08 g, 5.81 mmol) was dissolved in tetrahydrofuran (15 mL) and methanol (5 mL), and a 1N-aqueous solution of sodium hydroxide (11.60 mL, 11.60 mmol) was added thereto. The mixture was stirred for three hours at room temperature. The reaction liquor was poured onto ice-1N-hydrochloric acid, and precipitated solids were collected by filtration, and dried under reduced pressure, to obtain the title compound (1.70 g, 89%) as a solid.

Provenance & Evidence