反应详情

A solution of morpholin-4-yl-{4-[(2S)-4-((1R)-1-phenylethyl)-morpholin-2-yl]-phenyl}-methanone (465 mg, 1.20 mmol) and 20% palladium hydroxide on carbon (0.50 g) in ethanol (6.0 ml) was stirred under hydrogen atmosphere at room temperature for 10 hours. The mixture was passed through Celite column and the organic layer was concentrated under reduced pressure to yield morpholin-4-yl-((2S)-4-morpholin-2-yl-phenyl)-methanone (331 mg, 100%) as a clear oil.

1. concentrationthe organic layer was concentrated under reduced pressure