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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1091544Generated: November 2, 2026

Hydrochloric Acid → HCID 66594108, compound

https://huagongshe.com/reaction/1091544

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 57599804HCID 57599804—
SolventMethanolHCID 887—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66594108HCID 6659410889%

Reaction Steps

To a solution of N-imidazo[1,2-c]quinazolin-5-ylnicotinamide (40 mg, 0.14 mmol) in methanol (20 ml) was added a 4N solution of HCl in 1,4dioxane (0.5 ml). The mixture was concentrated under reduced pressure. The resulting solid was collected by filtration, washed with tetrahydrofurane and dried under reduced pressure to give N-imidazo[1,2-c]quinazolin-5-ylnicotinamide hydrochloride (40 mg, 89% yield) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08129386B2
Source datasetuspto-grants-2012_03
ORD IDord-ac3272be2c1140c19bc875face40ef49
Source noteuspto-grants-2012_03