HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[4-(3-Phenylpropyl)piperidin-1-yl]octan-3-one → 6-{2-[4-(3-Phenylpropyl)piperidin-1-yl]ethyl}undecan-6-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[4-(3-Phenylpropyl)piperidin-1-yl]octan-3-one | HCID 11537237 | — |
| Reactant | HCID 178445865 | HCID 178445865 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 6-{2-[4-(3-Phenylpropyl)piperidin-1-yl]ethyl}undecan-6-ol | HCID 11516925 | — |
Reaction Steps
1 equivalent of pentylmagnesium bromide was reacted with 1 equivalent of the compound obtained in Example 2, in anhydrous THF, under nitrogen, at room temperature. The product thus obtained was worked up and purified on a column of silica. The results of the NMR and mass spectrometry analyses were in accordance with the expected structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08129409B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-ed41e67c4c8746b18580eaeb8cf44201 |
| Source note | uspto-grants-2012_03 |