Dichloromethane → 7-chloro-6-[2-(cyclopropylmethyl-amino)-thiazol-5-ylthiomethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][c:11]2[c:12]([c:15]([CH2:20][S:21][c:22]3[cH:23][n:24][c:25]([NH:27][CH2:28][CH:29]4[CH2:30][CH2:31]4)[s:26]3)[c:16]([Cl:19])[cH:17][cH:18]2)[CH2:13][CH2:14]1)([CH3:5])([CH3:6])[CH3:7].[Cl:39][CH2:40][Cl:41].[OH:32][C:33]([C:34]([F:35])([F:36])[F:37])=[O:38]>>[NH:8]1[CH2:9][CH2:10][c:11]2[c:12]([c:15]([CH2:20][S:21][c:22]3[cH:23][n:24][c:25]([NH:27][CH2:28][CH:29]4[CH2:30][CH2:31]4)[s:26]3)[c:16]([Cl:19])[cH:17][cH:18]2)[CH2:13][CH2:14]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-10db3da6cada4f52b22e1d57ad9f3453
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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