HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1092296Generated: October 26, 2026
n-Heptyl isocyanate → 1-(6-Bromopyrid-2-yl)-1-methyl-3-heptylurea
https://huagongshe.com/reaction/1092296
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | n-Heptyl isocyanate | HCID 138341 | — |
| Reactant | 6-bromo-N-methylpyridin-2-amine | HCID 13470315 | — |
| Product | 1-(6-Bromopyrid-2-yl)-1-methyl-3-heptylurea | HCID 86018868 | 71% |
Reaction Steps
2 g of 6-methylamino-2-brompyridine (prepared according to the procedure of Example 11, step a) are mixed with 3.0 mL of heptyl isocyanate. The mixture is heated for 12 hours at 100° C. The residue is chromatographed on silica gel (9/1 heptane/ethyl acetate). 2.45 g of 1-(6-bromopyrid-2-yl)-1-methyl-3-heptylurea are obtained. Yield=71%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08129416B2 |
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| Source dataset | uspto-grants-2012_03 |
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| ORD ID | ord-34733b0d056e4caf96bbb6237126c44e |
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| Source note | uspto-grants-2012_03 |
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