Methyl iodide → HCID 24965502, compound

Participants

Reaction Steps

This material was obtained in analogy to the procedure outlined in example 23 from 1-adamantan-2-yl-4-(2,2,2-trifluoro-ethyl)-1,3-dihydro-imidazol-2-one (obtained in example 16, 100 mg) by alkylation with iodomethane (71 mg). 1-Adamantan-2-yl-3-methyl-4-(2,2,2-trifluoro-ethyl)-1,3-dihydro-imidazol-2-one was obtained as a light yellow solid (72 mg). MS (EI): 314.2 (M+).

Provenance & Evidence