(Bromomethyl)cyclobutane → HCID 24965852, compound

Participants

Reaction Steps

This material was obtained in analogy to the procedure outlined in example 23 from 4-isobutyl-1-(2-trifluoromethyl-phenyl)-1,3-dihydro-imidazol-2-one (obtained in example 18, 200 mg) by alkylation with bromomethylcyclobutane (115 mg). 3-Cyclobutylmethyl-4-isobutyl-1-(2-trifluoromethyl-phenyl)-1,3-dihydro-imidazol-2-one was obtained as a light yellow oil (9 mg). MS (ESI): 353.2 (MH+).

Provenance & Evidence