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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1092756Generated: November 2, 2026

HCID 86627645, compound → HCID 86627646, compound

https://huagongshe.com/reaction/1092756

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86627645HCID 86627645—
SolventMethanolHCID 887—
ProductHCID 86627646HCID 8662764699.9%

Reaction Steps

Crude 4-{5-chloro-2-[(2-chloro-pyridine-4-carbonyl)-amino]phenyl}-3,6-dihydro-2H-pyridine-1-carboxylic acid 1-chloro-ethyl ester (550 mg) was dissolved in methanol (25 ml) in and heated to reflux for 16 hours. Evaporation afforded the crude title product (465 mg). Retention Time HPLC 1.48 min; MS (ES+) 350, 348 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08129534B2
Source datasetuspto-grants-2012_03
ORD IDord-2f1f9c3d6f544c2385a526198379b0c5
Source noteuspto-grants-2012_03