1,2-Dibromoethane → HCID 66590094, compound

HRID 1092792Notes

Reaction equation

HRID 1092792 reaction equation
[Cl:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[C:4]([F:9])[C:3]=1[OH:10].[Br:11][CH2:12][CH2:13]Br>>[Br:11][CH2:12][CH2:13][O:10][C:3]1[C:2]([Cl:1])=[C:7]([F:8])[CH:6]=[CH:5][C:4]=1[F:9]

Participants

3

Reactant 2

HCID 78391,2-DibromoethaneHCID 27735612-Chloro-3,6-difluorophenol

Product 1

HCID 66590094HCID 66590094, compoundYield 31%

Procedure

2-Chloro-3,6-difluorophenol was reacted with 1,2-dibromoethane according to the procedure described in Step 2A to yield 2C (2.1 g, 31%). 1H NMR (400 MHz, CHLOROFORM-d) δ ppm 3.65 (t, J=6.57 Hz, 2H), 4.43 (t, J=6.57 Hz, 2H) 6.89 (m, 1H) 7.01 (m, 1H).

Sources & evidence

ORD record
ord-34757d213564454eaaf7a468328ec5a8
Source dataset
uspto-grants-2012_03
Patent number
US08129538B1

Reaction notes

Loading…