反应详情

Potassium thioacetate (93 mg, 0.81 mmol) was added to a solution of 100 mg (0.54 mmol) of (2R)-2-chloro-3-phenylpropionic acid in 2 ml of N-methyl-2-pyrrolidone at room temperature, and the mixture was stirred for 24 hours. The work-up procedure in the same manner as in Example 18 of the reaction mixture was followed to give 114 mg (0.51 mmol, yield 94%) of the desired (2S)-2-acetylthio-3-phenylpropionic acid.