Trifluoroacetic acid → HCID 57424681, compound

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Reaction Steps

A solution of tert-butyl 9-(6-(4-(3-(4-(2-(dimethylamino)ethoxy)phenyl)ureido)phenyl)-1-(2,2,2-trifluoroethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-3-oxa-7,9-diazabicyclo[3.3.1]nonane-7-carboxylate.TFA (174 mg) in dichloromethane (5 mL) was treated with trifluoroacetic acid (1 mL). After concentration, the residue was purified by reverse-phase high performance liquid chromatography to provide, after concentration, the title compound. MS (ES+): 626.3 (M+H)+

Provenance & Evidence