HuagongsheHuagongshe Chemistry Print Report · For research reference only
Urea → HCID 178518411, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Urea | HCID 1176 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-Aminothiophene-2-carboxamide | HCID 518993 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178518411 | HCID 178518411 | — |
Reaction Steps
50 mg (0.35 mmol) 3-amino-2-aminocarbonyl-thiophene is covered with urea. The urea is heated until molten. After 5 minutes of heating, the molten mixture is poured into 1 N NaOH (2 mL). Acetic acid is added to neutralize the mixture (pH 7) and the resulting white precipitate is collected. Yield: 39 mg (0.23 mmol, 66%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08129371B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-f43c7639e98c4c10b3a773188ddd6977 |
| Source note | uspto-grants-2012_03 |