HCID 57704605, compound → HCID 57704618, compound

Participants

Reaction Steps

Compound 51-3 (11.1 g) was dissolved in 1,4-dioxane (250 ml), 10% palladium carbon (3.5 g) was added, and the mixture was stirred under a hydrogen atmosphere at room temperature for 3.5 hr. The reaction container was purged with nitrogen, the solution was filtered, and the filtrate was concentrated. The residue was suspended in a mixed solution of diisopropyl ether and hexane and collected by filtration to give the object product (8.17 g) as a white powder.

Provenance & Evidence