Dimethylformamide → 1-[(3,4-Dichlorophenyl)methyl]-5-methyl-N-(4-{[2-(tetrahydro-2H-pyran-2-yloxy)ethyl]oxy}phenyl)-1H-1,2,3-triazole-4-carboxamide

HRID 109363Notes

Reaction equation

HRID 109363 reaction equation
[Cl:1][c:2]1[cH:3][c:4]([CH2:9][n:10]2[n:11][n:12][c:13]([C:16](=[O:17])[OH:18])[c:14]2[CH3:15])[cH:5][cH:6][c:7]1[Cl:8].[O:19]1[CH:20]([O:25][CH2:26][CH2:27][O:28][c:29]2[cH:30][cH:31][c:32]([NH2:33])[cH:34][cH:35]2)[CH2:21][CH2:22][CH2:23][CH2:24]1.[O:60]=[CH:61][N:62]([CH3:63])[CH3:64].[P-:36]([F:37])([F:38])([F:39])([F:40])([F:41])[F:42].[n:43]1([O:44][C:45]([N:46]([CH3:47])[CH3:48])=[N+:49]([CH3:50])[CH3:51])[c:52]2[n:53][cH:54][cH:55][cH:56][c:57]2[n:58][n:59]1>>[Cl:1][c:2]1[cH:3][c:4]([CH2:9][n:10]2[n:11][n:12][c:13]([C:16](=[O:18])[NH:33][c:32]3[cH:31][cH:30][c:29]([O:28][CH2:27][CH2:26][O:25][CH:20]4[O:19][CH2:24][CH2:23][CH2:22][CH2:21]4)[cH:35][cH:34]3)[c:14]2[CH3:15])[cH:5][cH:6][c:7]1[Cl:8]

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 110209174-[2-(Oxan-2-yloxy)ethoxy]anilineHCID 550298731-(3,4-dichlorobenzyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid

Product 1

HCID 595834191-[(3,4-Dichlorophenyl)methyl]-5-methyl-N-(4-{[2-(tetrahydro-2H-pyran-2-yloxy)ethyl]oxy}phenyl)-1H-1,2,3-triazole-4-carboxamide

Sources & evidence

ORD record
ord-207ad23439b64371bba41cc58d54d225
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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