HCID 66637581, compound → HCID 66637583, compound

Participants

Reaction Steps

To a solution of crude N-t-butoxycarbonyl-(S)-2-amino-5-(1-piperidinyl)pentanoic acid benzyl ester in ethanol (1.5 mL) was added 5% palladium-carbon (15.0 mg) and the mixture was stirred for 1 hour under hydrogen atmosphere. The insoluble materials were removed by suction filtration using selite, and the residue was washed with ethanol (10 mL). The filtrate and washings were collected and concentrated under vacuum to obtain crude N-t-butoxycarbonyl-(S)-2-amino-5-(1-piperidinyl)pentanoic acid (69.0 mg) as a colorless oily material.

Provenance & Evidence