Ethylenediamine → 3-(benzyloxy)-1-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]cyclobutylacetonitrile
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH:9]1[CH2:10][C:11]([n:13]2[n:14][cH:15][c:16](-[c:18]3[c:19]4[c:20]([n:21][cH:22][n:23]3)[n:24]([CH2:27][O:28][CH2:29][CH2:30][Si:31]([CH3:32])([CH3:33])[CH3:34])[cH:25][cH:26]4)[cH:17]2)([CH2:35][C:36]#[N:37])[CH2:12]1.[NH2:45][CH2:46][CH2:47][NH2:48].[OH:38][C:39]([C:40]([F:41])([F:42])[F:43])=[O:44]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH:9]1[CH2:10][C:11]([n:13]2[n:14][cH:15][c:16](-[c:18]3[c:19]4[c:20]([n:21][cH:22][n:23]3)[nH:24][cH:25][cH:26]4)[cH:17]2)([CH2:35][C:36]#[N:37])[CH2:12]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-f14af8320315412aac4663329322d263
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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