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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1094265Generated: November 1, 2026

2-(3,4-dimethylphenyl)benzoic Acid → (R)-[3-(5-Bromo-pyrimidin-2-ylamino)-piperidin-1-yl]-(3',4'-dimethyl-biphenyl-2-yl)-methanone

https://huagongshe.com/reaction/1094265

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3,4-dimethylphenyl)benzoic AcidHCID 2758545—
ReactantHCID 66639492HCID 66639492—
Product(R)-[3-(5-Bromo-pyrimidin-2-ylamino)-piperidin-1-yl]-(3',4'-dimethyl-biphenyl-2-yl)-methanoneHCID 24963402—

Reaction Steps

prepared by reaction of 3′,4′-dimethyl-biphenyl-2-carboxylic acid with (R)-(5-bromo-pyrimidin-2-yl)-piperidine-3-yl-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08133901B2
Source datasetuspto-grants-2012_03
ORD IDord-e01481076d0446ce87bb4e970cd94f71
Source noteuspto-grants-2012_03