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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1094309Generated: October 27, 2026

5-Propylthiophene-2-carboxylic acid → 2-Ethyl-6-methyl-4-[5-(5-propyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-phenol

https://huagongshe.com/reaction/1094309

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Propylthiophene-2-carboxylic acidHCID 3164314—
ReactantHCID 178436626HCID 178436626—
Product2-Ethyl-6-methyl-4-[5-(5-propyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-phenolHCID 136029942—

Reaction Steps

2-Ethyl-6-methyl-4-[5-(5-propyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-phenol is prepared in analogy to Example 1 starting from 5-propyl-thiophene-2-carboxylic acid and 3-ethyl-4,N-dihydroxy-5-methyl-benzamidine; LC-MS: tR=1.12 min, [M+1]+=329.14.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08133910B2
Source datasetuspto-grants-2012_03
ORD IDord-46f4b53e6ca14fd8bf9d8a2f832a4963
Source noteuspto-grants-2012_03