HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxo(pyridin-3-yl)acetic acid → HCID 58007490, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxo(pyridin-3-yl)acetic acid | HCID 13548099 | — |
| Reactant | (3,4-Dimethyl-phenyl)-[2-(6-trifluoromethyl-pyridin-3-yl)-ethyl]-amine | HCID 58007591 | — |
| Product | HCID 58007490 | HCID 58007490 | 27% |
Reaction Steps
In analogy to example 7, (3,4-dimethyl-phenyl)-[2-(6-trifluoromethyl-pyridin-3-yl)-ethyl]-amine (250 mg, 0.85 mmol) and oxo-pyridin-3-yl-acetic acid (343 mg, 1.27 mmol, CAS 39684-37-2) were coupled together to afford the title compound (48 mg, 27%) as a colourless solid. MS m/e: 430.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08133909B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-f19bf898ec6c46939d271b566d25fb89 |
| Source note | uspto-grants-2012_03 |