HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 2-methoxy-1-methyl-4-nitro- → HCID 58007507, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 2-methoxy-1-methyl-4-nitro- | HCID 83159 | — |
| Reactant | 3-Pyridineacetonitrile, 6-(trifluoromethyl)- | HCID 50851127 | — |
| Product | HCID 58007507 | HCID 58007507 | 31.3% |
Reaction Steps
In analogy to example 6, step 1, 2-methoxy-1-methyl-4-nitro-benzene (988 mg, 5.91 mmol) was coupled to (6-trifluoromethyl-pyridin-3-yl)-acetonitrile (1.0 g, 5.37 mmol, prepared in example 1, step 1) to give the title compound (521 mg, 31%) as an orange oil MS m/e: 311.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08133909B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-5bbc0af40c464663bb4942e754a22f99 |
| Source note | uspto-grants-2012_03 |