HRID1094366

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11010409

Boc-Phg-OH

C13H17NO4

HCID58007501

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(N(CCc2ccc(C(F)(F)F)cn2)C(=O)[C@@H](NC(=O)OC(C)(C)C)c2ccccc2)cc1C

HCID58007549

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described for the synthesis example 21, step 3, the title compound was prepared from (3,4-dimethyl-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine and boc-L-alpha-phenylglycine. MS (m/e): 528.3 [M+H]+.

WORKUP

后处理

customIn analogy to the procedure described for the synthesis example 21, step 3

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ce17f0032b964c4494258ee76fba690e
来源数据集: uspto-grants-2012_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08133909B2
来源说明: uspto-grants-2012_03

反应 SMILES

[CH3:1][C:2]1[CH:3]=[C:4]([NH:9][CH2:10][CH2:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][N:13]=2)[CH:5]=[CH:6][C:7]=1[CH3:8].[CH3:22][C:23]([O:26][C:27]([NH:29][C@H:30]([C:37](O)=[O:38])[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)=[O:28])([CH3:25])[CH3:24]>>[C:23]([O:26][C:27](=[O:28])[NH:29][C@H:30]([C:37](=[O:38])[N:9]([C:4]1[CH:5]=[CH:6][C:7]([CH3:8])=[C:2]([CH3:1])[CH:3]=1)[CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][N:13]=1)[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)([CH3:25])([CH3:22])[CH3:24]