HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-(((tert-butoxy)carbonyl)amino)-2-phenylacetic acid → ((s)-{(3,4-Dimethyl-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-carbamoyl}-phenyl-methyl)-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-(((tert-butoxy)carbonyl)amino)-2-phenylacetic acid | HCID 11010409 | — |
| Reactant | (3,4-Dimethyl-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine | HCID 58007501 | — |
| Product | ((s)-{(3,4-Dimethyl-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-carbamoyl}-phenyl-methyl)-carbamic acid tert-butyl ester | HCID 58007549 | — |
Reaction Steps
In analogy to the procedure described for the synthesis example 21, step 3, the title compound was prepared from (3,4-dimethyl-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine and boc-L-alpha-phenylglycine. MS (m/e): 528.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08133909B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-ce17f0032b964c4494258ee76fba690e |
| Source note | uspto-grants-2012_03 |