HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → N-Benzothiazol-6-yl-2-(2-methoxy-phenyl)-N-[2-(4-trifluoromethyl-phenyl)-ethyl]-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 2-Methoxyphenylacetic acid | HCID 7134 | — |
| Reactant | Benzothiazol-6-yl-[2-(4-trifluoromethyl-phenyl)-ethyl]-amine | HCID 57570295 | — |
| Product | N-Benzothiazol-6-yl-2-(2-methoxy-phenyl)-N-[2-(4-trifluoromethyl-phenyl)-ethyl]-acetamide | HCID 57570438 | — |
Reaction Steps
In analogy to example 33, step 2, without TFA addition, benzothiazol-6-yl-[2-(4-trifluoromethyl-phenyl)-ethyl]-amine was coupled to (2-methoxy-phenyl)-acetic acid (commercially available) to provide the title compound. MS m/e: 471.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08133909B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-1b26131514e54675940b9a07ae7ae50c |
| Source note | uspto-grants-2012_03 |