HuagongsheHuagongshe Chemistry Print Report · For research reference only
(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid → [2-(4-Trifluoromethyl-phenyl)-ethyl]-(6-trifluoromethyl-pyridin-3-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid | HCID 118342 | — |
| Reactant | 5-Amino-2-(trifluoromethyl)pyridine | HCID 2737744 | — |
| Product | [2-(4-Trifluoromethyl-phenyl)-ethyl]-(6-trifluoromethyl-pyridin-3-yl)-amine | HCID 58007513 | — |
Reaction Steps
In analogy to example 33, step 1, (4-trifluoromethyl-phenyl)-acetic acid (commercially available) was coupled with 6-trifluoromethyl-pyridin-3-ylamine (commercially available) to give the title compound MS m/e: 335.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08133909B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-fc62bdcb9d5545a6902b6583d4dcb58b |
| Source note | uspto-grants-2012_03 |