5-Amino-2-methylpyridine → N-(6-methyl-pyridin-3-yl)-2-oxo-2-phenyl-acetamide

HRID 1094385Notes

Reaction equation

HRID 1094385 reaction equation
[CH3:1][C:2]1[N:7]=[CH:6][C:5]([NH2:8])=[CH:4][CH:3]=1.[C:9]([C:17](Cl)=[O:18])(=[O:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH3:1][C:2]1[N:7]=[CH:6][C:5]([NH:8][C:17](=[O:18])[C:9](=[O:16])[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 2433135-Amino-2-methylpyridineHCID 110842942-Oxo-2-phenylacetyl chloride

Product 1

HCID 58007594N-(6-methyl-pyridin-3-yl)-2-oxo-2-phenyl-acetamide

Procedure

In analogy to the procedure described for the synthesis example 41 (step 1), the title compound N-(6-methyl-pyridin-3-yl)-2-oxo-2-phenyl-acetamide (MS m/e: 241.2 [M+H]+) was prepared from 6-methyl-pyridin-3-ylamine and benzoylformic acid chloride.

Workup

  1. customIn analogy to the procedure described for the synthesis example 41 (step 1)

Sources & evidence

ORD record
ord-e1eab7a753a74ab6b33bfc1f14e5809a
Source dataset
uspto-grants-2012_03
Patent number
US08133909B2

Reaction notes

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