4-Amino-2-methylpyridine → HCID 58007539, compound

HRID 1094389Notes

Reaction equation

HRID 1094389 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([CH3:8])[CH:3]=1.[C:9]([C:17](Cl)=[O:18])(=[O:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH3:8][C:4]1[CH:3]=[C:2]([NH:1][C:17](=[O:18])[C:9](=[O:16])[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:7]=[CH:6][N:5]=1

Participants

3

Reactant 2

HCID 7286704-Amino-2-methylpyridineHCID 110842942-Oxo-2-phenylacetyl chloride

Product 1

HCID 58007539HCID 58007539, compound

Procedure

In analogy to the procedure described for the synthesis example 41 (step 1), the title compound N-(2-methyl-pyridin-4-yl)-2-oxo-2-phenyl-acetamide (MS m/e: 241.2 [M+H]+) was prepared from 4-amino-2-picoline and benzoylformic acid chloride.

Workup

  1. customIn analogy to the procedure described for the synthesis example 41 (step 1)

Sources & evidence

ORD record
ord-4aa516d5231449dea7c09880550b060b
Source dataset
uspto-grants-2012_03
Patent number
US08133909B2

Reaction notes

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