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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1094417Generated: November 1, 2026

Indan-5-amine → Indan-5-yl-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine

https://huagongshe.com/reaction/1094417

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndan-5-amineHCID 90496—
Reactant5-(Trifluoromethyl)-2-vinylpyridineHCID 58933992—
ProductIndan-5-yl-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amineHCID 66637455—

Reaction Steps

In analogy to the procedure described for the synthesis example 25 (step 1), the title compound Indan-5-yl-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine (MS m/e: 307.2 [M+H]+) was prepared from 5-amino-indan instead of 3,4-dimethylaniline and 5-trifluoromethyl-2-vinyl-pyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08133909B2
Source datasetuspto-grants-2012_03
ORD IDord-5b9e3e3c5d974a0094c68b27e085f85f
Source noteuspto-grants-2012_03