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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1094419Generated: November 1, 2026

5-Bromo-2,3-dihydro-1-benzofuran → HCID 58007496, compound

https://huagongshe.com/reaction/1094419

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2,3-dihydro-1-benzofuranHCID 2776159—
Reactant2-(5-Trifluoromethyl-pyridin-2-YL)-ethylamineHCID 18071344—
ProductHCID 58007496HCID 58007496—

Reaction Steps

In analogy to the procedure described for the synthesis example 71 (step 1), the title compound (2,3-dihydro-benzofuran-5-yl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine (MS m/e: 309.0 [M+H]+) was prepared from 5-bromo-2,3-dihydro-1-benzofuran instead of 6-bromo-2,3-dihydro-benzofuran and 2-(5-trifluoromethyl-pyridin-2-yl)-ethylamine instead of 2-(6-trifluoromethyl-pyridin-3-yl)-ethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08133909B2
Source datasetuspto-grants-2012_03
ORD IDord-553f8e4769794c8ea21d9f73892b414c
Source noteuspto-grants-2012_03