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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1094428Generated: October 31, 2026

1-Bromo-4-cyclopropylbenzene → HCID 58007557, compound

https://huagongshe.com/reaction/1094428

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-4-cyclopropylbenzeneHCID 12221355—
Reactant2-(5-Trifluoromethyl-pyridin-2-YL)-ethylamineHCID 18071344—
ProductHCID 58007557HCID 58007557—

Reaction Steps

In analogy to the procedure described for the synthesis example 71 (step 1), the title compound (4-cyclopropyl-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine (MS m/e: 307.2 [M+H]+) was prepared from 1-bromo-4-cyclopropyl-benzene instead of 6-bromo-2,3-dihydro-benzofuran and 2-(5-trifluoromethyl-pyridin-2-yl)-ethylamine instead of 2-(6-trifluoromethyl-pyridin-3-yl)-ethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08133909B2
Source datasetuspto-grants-2012_03
ORD IDord-8de98918bfa34ceba303994f19e333a5
Source noteuspto-grants-2012_03