HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(5-Trifluoromethyl-pyridin-2-YL)-ethylamine → (3,4-Bis-difluoromethoxy-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(5-Trifluoromethyl-pyridin-2-YL)-ethylamine | HCID 18071344 | — |
| Reactant | HCID 66637781 | HCID 66637781 | — |
| Product | (3,4-Bis-difluoromethoxy-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine | HCID 58007488 | — |
Reaction Steps
In analogy to the procedure described for the synthesis example 71 (step 1), the title compound (3,4-bis-difluoromethoxy-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine (MS m/e: 399.1 [M+H]+) was prepared from 1,2-bis-difluoromethoxy-4-iodo-benzene instead of 6-bromo-2,3-dihydro-benzofuran and 2-(5-trifluoromethyl-pyridin-2-yl)-ethylamine instead of 2-(6-trifluoromethyl-pyridin-3-yl)-ethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08133909B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-3a6bf196eadf464c91ab6b9eabf2afc2 |
| Source note | uspto-grants-2012_03 |